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- Title
The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction.
- Authors
Rahaghi, Franck F; Sandhaus, Robert A; Brantly, Mark L; Rouhani, Farshid; Campos, Michael A; Strange, Charlie; Hogarth, Douglas Kyle; Eden, Edward; Stocks, James M; Krowka, Michael J; Stoller, James K
- Abstract
Alpha-1 antitrypsin deficiency (AATD) is a genetic disease that may be manifested by chronic obstructive pulmonary disease. Despite professional society guidelines that recommend broad testing of at-risk individuals, fewer than 10% of affected individuals have been identified. The goals of this study were to estimate the frequency of abnormal AAT genotypes among patients found to have fixed airflow obstruction and to assess the feasibility of having Pulmonary Function Laboratory personnel administer the study.
- Publication
COPD, 2012, Vol 9, Issue 4, p352
- ISSN
1541-2563
- Publication type
Journal Article
- DOI
10.3109/15412555.2012.669433