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- Title
Anti-inflammatory, analgesic, and antipyretic activities of virgin coconut oil.
- Authors
Intahphuak, S; Khonsung, P; Panthong, A
- Abstract
This study investigated some pharmacological properties of virgin coconut oil (VCO), the natural pure oil from coconut [Cocos nucifera Linn (Palmae)] milk, which was prepared without using chemical or high-heat treatment. The anti-inflammatory, analgesic, and antipyretic effects of VCO were assessed. In acute inflammatory models, VCO showed moderate anti-inflammatory effects on ethyl phenylpropiolate-induced ear edema in rats, and carrageenin- and arachidonic acid-induced paw edema. VCO exhibited an inhibitory effect on chronic inflammation by reducing the transudative weight, granuloma formation, and serum alkaline phosphatase activity. VCO also showed a moderate analgesic effect on the acetic acid-induced writhing response as well as an antipyretic effect in yeast-induced hyperthermia. The results obtained suggest anti-inflammatory, analgesic, and antipyretic properties of VCO.
- Publication
Pharmaceutical biology, 2010, Vol 48, Issue 2, p151
- ISSN
1744-5116
- Publication type
Journal Article
- DOI
10.3109/13880200903062614