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Title
Activation of NF-κB in placentas of women with preeclampsia.
Authors
Vaughan, John E; Walsh, Scott W
Abstract
Placentas are oxidatively stressed during preeclampsia and produce more tumor necrosis factor α (TNFα) and more thromboxane than normal. Oxidative stress may cause these abnormalities by activating nuclear factor-κB (NF-κB). We measured the levels of activated NF-κB in normal and preeclamptic placentas and determined whether oxidative stress activates NF-κB in a trophoblast-like cell line.
Publication
Hypertension in pregnancy, 2012, Vol 31, Issue 2, p243