We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Retinal pigment epithelial cells induce foxp3(+) regulatory T cells via membrane-bound TGF-β.
- Authors
Vega, Jose L; Saban, Daniel; Carrier, Yejun; Masli, Sharmila; Weiner, Howard L
- Abstract
It is speculated that retinal pigment epithelial (RPE) cells convert naïve T cells into regulatory T cells (Tregs) via soluble factors such as transforming growth factor beta (TGF-β). Yet presence or absence of similar membrane-bound mechanisms on RPE cells has yet to be addressed. Here the authors investigated the expression of surface TGF-β by RPE cells and its participation in the conversion of naive T cells into Tregs.
- Publication
Ocular immunology and inflammation, 2010, Vol 18, Issue 6, p459
- ISSN
1744-5078
- Publication type
Journal Article
- DOI
10.3109/09273948.2010.509532