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- Title
Ginsenoside Rh2-B1 stimulates cell proliferation and IFN-γ production by activating the p38 MAPK and ERK-dependent signaling pathways in CTLL-2 cells.
- Authors
Lv, Shuang; Yi, Peng-Fei; Shen, Hai-Qing; Zhang, Li-Yan; Dong, Hai-Bing; Wu, Shuai-Cheng; Xia, Fang; Guo, Xun; Wei, Xu-Bin; Fu, Ben-Dong
- Abstract
Ginsenoside Rh2, an active component of ginseng, exhibits immunoregulatory and anti-inflammatory properties. Rh2-B1, a sulfated derivative, was prepared to enhance its water solubility. We studied the effect of Rh2-B1 on CTLL-2, a CD8⁺ cytotoxic T cell line that was known for protecting against viral infection.
- Publication
Immunopharmacology and immunotoxicology, 2014, Vol 36, Issue 1, p43
- ISSN
1532-2513
- Publication type
Journal Article
- DOI
10.3109/08923973.2013.864669