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- Title
New clues in celiac disease epidemiology, pathogenesis, clinical manifestations, and treatment.
- Authors
Lionetti, Elena; Catassi, Carlo
- Abstract
Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. It is one of the most common lifelong disorders on a worldwide basis. Celiac enteropathy is the final consequence of an abnormal immune reaction, showing features of both an innate and an adaptive response to gluten prolamins. The clinical spectrum is wide, including cases with either typical intestinal or atypical extraintestinal features, and silent forms. The only available treatment consists in dietary exclusion of grains containing gluten. New pharmacological treatment are currently under scrutiny.
- Publication
International reviews of immunology, 2011, Vol 30, Issue 4, p219
- ISSN
1563-5244
- Publication type
Journal Article
- DOI
10.3109/08830185.2011.602443