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- Title
Plexiform fibrohistiocytic tumor: ultrastructural studies may aid in discrimination from cellular neurothekeoma.
- Authors
Wartchow, Eric P; Goin, Luann; Schreiber, Jillian; Mierau, Gary W; Terella, Adam; Allen, Gregory C
- Abstract
Plexiform fibrohistiocytic tumor is a low-grade soft tissue malignancy that can at times be difficult to differentiate from the less biologically aggressive cellular neurothekeoma. The two entities, which may display identical clinical and histological features, cannot be distinguished by immunohistochemical or molecular diagnostic means. Electron microscopy may enable the accurate identification of problematic examples and thus aid in resolving these occasionally occurring diagnostic dilemmas. To illustrate typical variations in the ultrastructural appearance of plexiform fibrohistiocytic tumor, the authors present two diagnostically noncontroversial examples, and to demonstrate the potential diagnostic utility of electron microscopy in this setting, they present an example of plexiform fibrohistiocytic tumor that could not otherwise have been distinguished from cellular neurothekeoma.
- Publication
Ultrastructural pathology, 2009, Vol 33, Issue 6, p286
- ISSN
1521-0758
- Publication type
Journal Article
- DOI
10.3109/01913120903348860