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- Title
New approach to quantification of molecularly targeted radiotracer uptake from hybrid cardiac SPECT/CT: methodology and validation.
- Authors
Li, Shimin; Sinusas, Albert J; Dobrucki, Lawrence W; Liu, Yi-Hwa
- Abstract
Quantification of molecularly targeted radiotracer uptake in the myocardium from SPECT remains challenging in part due to potentially low levels of focal tracer uptake of presently available molecularly targeted agents and further degradation of cardiac SPECT by extracardiac radioactivity and partial-volume effect. The purpose of this study was to derive and validate a new SPECT quantification method for assessments of absolute radiotracer uptake in the myocardium.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Vol 54, Issue 12, p2175
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.113.123208