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- Title
Targeting of endothelin receptors in the healthy and infarcted rat heart using the PET tracer 18F-FBzBMS.
- Authors
Higuchi, Takahiro; Rischpler, Christoph; Fukushima, Kenji; Isoda, Takuro; Xia, Jinsong; Javadi, Mehrbod S; Szabo, Zsolt; Dannals, Robert F; Mathews, William B; Bengel, Frank M
- Abstract
The endothelin subtype-A receptor (ET-A) is a promising therapeutic target in cardiovascular disease. We sought to determine the feasibility of an (18)F-labeled ligand, (18)F-(N-[[29-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,19-biphenyl]-2-yl]methyl]-N,4-fluorobenzamide) ((18)F-FBzBMS), for imaging ET-A in the healthy and injured rat heart.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Vol 54, Issue 2, p277
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.112.106096