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- Title
PET and MRI reveal early evidence of neurodegeneration in spinocerebellar ataxia type 17.
- Authors
Brockmann, Kathrin; Reimold, Matthias; Globas, Christoph; Hauser, Till Karsten; Walter, Uwe; Machulla, Hans-Jürgen; Rolfs, Arndt; Schöls, Ludger
- Abstract
Spinocerebellar ataxia type 17 (SCA17) is a rare autosomal dominantly inherited neurodegenerative disorder presenting with a variable phenotype including ataxia, dystonia, chorea, and parkinsonism, as well as cognitive impairment. We evaluated morphologic and functional imaging characteristics to elucidate evidence of neurodegeneration in SCA17, even in the presymptomatic stage of the disease.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Vol 53, Issue 7, p1074
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.111.101543