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- Title
Antitumor effects of proteasome inhibition in anaplastic thyroid carcinoma.
- Authors
Altmann, Annette; Markert, Annette; Askoxylakis, Vasileios; Schöning, Tilman; Jesenofsky, Ralf; Eisenhut, Michael; Haberkorn, Uwe
- Abstract
The ubiquitin-proteasome pathway has been identified as a potential molecular target for cancer therapy. In this study, we investigated the effect of the proteasome inhibitor bortezomib on anaplastic thyroid carcinoma (ATC) characterized by complete refractoriness to multimodal therapeutic approaches.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Vol 53, Issue 11, p1764
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.111.101295