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- Title
Molecular imaging with 11C-PD153035 PET/CT predicts survival in non-small cell lung cancer treated with EGFR-TKI: a pilot study.
- Authors
Meng, Xue; Loo, Billy W, Jr; Ma, Li; Murphy, James D; Sun, Xindong; Yu, Jinming
- Abstract
Outcomes are suboptimal when molecularly targeted therapies are used in patient populations unselected for the molecular target. This pilot study examines the correlation of PET using (11)C-labeled 4-N-(3-bromoanilino)-6,7-dimethoxyquinazoline ((11)C-PD153035), an imaging biomarker of epidermal growth factor receptor (EGFR), with outcomes in patients with non-small cell lung cancer (NSCLC) treated with the EGFR tyrosine kinase inhibitor erlotinib.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Vol 52, Issue 10, p1573
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.111.092874