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- Title
A beta-camera integrated with a microfluidic chip for radioassays based on real-time imaging of glycolysis in small cell populations.
- Authors
Vu, Nam T; Yu, Zeta T F; Comin-Anduix, Begonya; Søndergaard, Jonas N; Silverman, Robert W; Chang, Canny Y N; Ribas, Antoni; Tseng, Hsian-Rong; Chatziioannou, Arion F
- Abstract
An integrated β-camera and microfluidic chip was developed that is capable of quantitative imaging of glycolysis radioassays using (18)F-FDG in small cell populations down to a single cell. This paper demonstrates that the integrated system enables digital control and quantitative measurements of glycolysis in B-Raf(V600E)-mutated melanoma cell lines in response to specific B-Raf inhibition.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Vol 52, Issue 5, p815
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.110.078725