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- Title
Targeting prostate cancer cells in vivo using a rapidly internalizing novel human single-chain antibody fragment.
- Authors
He, Jiang; Wang, Yong; Feng, Jinjin; Zhu, Xiaodong; Lan, Xiaoli; Iyer, Arun K; Zhang, Niu; Seo, Youngho; VanBrocklin, Henry F; Liu, Bin
- Abstract
Human antibodies targeting prostate cancer cell surface epitopes may be useful for imaging and therapy. The objective of this study was to evaluate the tumor targeting of an internalizing human antibody fragment, a small-size platform, to provide high contrast in a mouse model of human prostate carcinoma.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Vol 51, Issue 3, p427
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.109.069492