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- Title
In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18).
- Authors
Wong, Dean F; Rosenberg, Paul B; Zhou, Yun; Kumar, Anil; Raymont, Vanessa; Ravert, Hayden T; Dannals, Robert F; Nandi, Ayon; Brasić, James R; Ye, Weiguo; Hilton, John; Lyketsos, Constantine; Kung, Hank F; Joshi, Abhinay D; Skovronsky, Daniel M; Pontecorvo, Michael J
- Abstract
An (18)F-labeled PET amyloid-beta (Abeta) imaging agent could facilitate the clinical evaluation of late-life cognitive impairment by providing an objective measure for Alzheimer disease (AD) pathology. Here we present the results of a clinical trial with (E)-4-(2-(6-(2-(2-(2-(18)F-fluoroethoxy)ethoxy)ethoxy)pyridin-3-yl)vinyl)-N-methyl benzenamine ((18)F-AV-45 or florbetapir [corrected] F 18).
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Vol 51, Issue 6, p913
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.109.069088