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- Title
Melanin-targeted preclinical PET imaging of melanoma metastasis.
- Authors
Ren, Gang; Miao, Zheng; Liu, Hongguang; Jiang, Lei; Limpa-Amara, Naengnoi; Mahmood, Ashfaq; Gambhir, Sanjiv S; Cheng, Zhen
- Abstract
Dialkylamino-alkyl-benzamides possess an affinity for melanin, suggesting that labeling of such benzamides with (18)F could potentially produce melanin-targeted PET probes able to identify melanotic melanoma metastases in vivo with high sensitivity and specificity.
- Publication
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2009, Vol 50, Issue 10, p1692
- ISSN
1535-5667
- Publication type
Journal Article
- DOI
10.2967/jnumed.109.066175