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- Title
Reliability of basophil activation test using CD203c expression in diagnosis of pollen allergy.
- Authors
Özdemir, Seçil Kepil; Güloğlu, Deniz; Sin, Betül A; Elhan, Atilla H; Ikincioğulları, Aydan; Mısırlıgil, Zeynep
- Abstract
CD203c is a basophil surface marker and its expression is rapidly up-regulated after cross-linking of high-affinity immunoglobulin E (IgE) receptor (FcepsilonR1) by an allergen. CD203c basophil activation tests have been studied for the in vitro diagnosis of several allergic conditions. However, there is limited data about its diagnostic usefulness. The optimum allergen concentrations for stimulation and allergen specific cutoff values remain unknown for a number of allergens. This study was designed to investigate the efficacy of basophil activation test via CD203c in the diagnosis of pollen allergy.
- Publication
American journal of rhinology & allergy, 2011, Vol 25, Issue 6, pe225
- ISSN
1945-8932
- Publication type
Journal Article
- DOI
10.2500/ajra.2011.25.3723