We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Altered sinonasal ciliary dynamics in chronic rhinosinusitis.
- Authors
Chen, Bei; Shaari, Jeffrey; Claire, Steven Eau; Palmer, James N; Chiu, Alexander G; Kennedy, David W; Cohen, Noam A
- Abstract
Although multiple etiologies contribute to the development of rhinosinusitis, a common pathophysiological sequelae is ineffective sinonasal mucociliary clearance, resulting in stasis of sinonasal secretions, with subsequent infection, and persistent inflammation. The respiratory cilia beat continually at a basal rate, while during times of stress, such as exercise or infection, ciliary beat frequency (CBF) increases, accelerating mucus clearance. Previous investigations have led to conflicting results with some authors reporting decreased CBF while others have found normal values of CBF in patients with chronic rhinosinusitis (CRS). Additionally, these studies have only analyzed basal CBF. The goal of this study was to compare the basal as well as the stimulated sinonasal CBF in patients with CRS versus controls.
- Publication
American journal of rhinology, 2006, Vol 20, Issue 3, p325
- ISSN
1050-6586
- Publication type
Journal Article
- DOI
10.2500/ajr.2006.20.2870