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- Title
Kynurenine and its metabolites in Alzheimer's disease patients.
- Authors
Gulaj, E; Pawlak, K; Bien, B; Pawlak, D
- Abstract
The kynurenine pathway (KP) is a major route of tryptophan metabolism. Several metabolites of this pathway are proposed to be involved in the pathogenesis of Alzheimer's disease. The aim of this study was to evaluate peripheral KP in patients with Alzheimer type dementia and a detailed analysis of correlation between kynurenine (KYN), kynurenic acid (KYNA), 3-hydroxykynurenine (3-HK), anthranilic acid (AA), quinolinic acid (QUIN) and degree of neuropsychological changes in AD.
- Publication
Advances in medical sciences, 2010, Vol 55, Issue 2, p204
- ISSN
1898-4002
- Publication type
Journal Article
- DOI
10.2478/v10039-010-0023-6