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- Title
Emerging clinical importance of the cancer biomarkers kallikrein-related peptidases (KLK) in female and male reproductive organ malignancies.
- Authors
Schmitt, Manfred; Magdolen, Viktor; Yang, Feng; Kiechle, Marion; Bayani, Jane; Yousef, George M; Scorilas, Andreas; Diamandis, Eleftherios P; Dorn, Julia
- Abstract
Tumor tissue-associated KLKs (kallikrein-related peptidases) are clinically important biomarkers that may allow prognosis of the cancer disease and/or prediction of response/failure of cancer patients to cancer-directed drugs. Regarding the female/male reproductive tract, remarkably, all of the fifteen KLKs are expressed in the normal prostate, breast, cervix uteri, and the testis, whereas the uterus/endometrium and the ovary are expressing a limited number of KLKs only.
- Publication
Radiology and oncology, 2013, Vol 47, Issue 4, p319
- ISSN
1318-2099
- Publication type
Journal Article
- DOI
10.2478/raon-2013-0053