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- Title
Caffeine can decrease insulin sensitivity in humans.
- Authors
Keijzers, Gerben B; De Galan, Bastiaan E; Tack, Cees J; Smits, Paul
- Abstract
Caffeine is a central stimulant that increases the release of catecholamines. As a component of popular beverages, caffeine is widely used around the world. Its pharmacological effects are predominantly due to adenosine receptor antagonism and include release of catecholamines. We hypothesized that caffeine reduces insulin sensitivity, either due to catecholamines and/or as a result of blocking adenosine-mediated stimulation of peripheral glucose uptake.
- Publication
Diabetes care, 2002, Vol 25, Issue 2, p364
- ISSN
0149-5992
- Publication type
Journal Article
- DOI
10.2337/diacare.25.2.364