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- Title
A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes.
- Authors
Viberti, Giancarlo; Kahn, Steven E; Greene, Douglas A; Herman, William H; Zinman, Bernard; Holman, Rury R; Haffner, Steven M; Levy, Daniel; Lachin, John M; Berry, Rhona A; Heise, Mark A; Jones, Nigel P; Freed, Martin I
- Abstract
Therapies with metformin, sulfonylureas, or insulin improve glycemic control in the short term but do not prevent progressive islet beta-cell failure or long-term deterioration in glycemia. Our goal was to evaluate, in patients recently diagnosed with type 2 diabetes (<3 years), the long-term efficacy of monotherapy with rosiglitazone on glycemic control and on the progression of pathophysiological abnormalities associated with type 2 diabetes as compared with metformin or glyburide monotherapy.
- Publication
Diabetes care, 2002, Vol 25, Issue 10, p1737
- ISSN
0149-5992
- Publication type
Journal Article
- DOI
10.2337/diacare.25.10.1737