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- Title
Bromocriptine: a novel approach to the treatment of type 2 diabetes.
- Authors
Pijl, H; Ohashi, S; Matsuda, M; Miyazaki, Y; Mahankali, A; Kumar, V; Pipek, R; Iozzo, P; Lancaster, J L; Cincotta, A H; DeFronzo, R A
- Abstract
In vertebrates, body fat stores and insulin action are controlled by the temporal interaction of circadian neuroendocrine oscillations. Bromocriptine modulates neurotransmitter action in the brain and has been shown to improve glucose tolerance and insulin resistance in animal models of obesity and diabetes. We studied the effect of a quick-release bromocriptine formulation on glucose homeostasis and insulin sensitivity in obese type 2 diabetic subjects.
- Publication
Diabetes care, 2000, Vol 23, Issue 8, p1154
- ISSN
0149-5992
- Publication type
Journal Article
- DOI
10.2337/diacare.23.8.1154