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Title
GLUT2 in pancreatic islets.
Authors
Zhiyong Wang; Gleichmann, Helga
Abstract
Presents a model of experimentally autoimmune diabetes induced by multiple low doses of streptozotocin (MLD-STZ). Development of diabetes upon the induction of both beta-cell toxicity and T-cell-dependent immune reactions; GLUT2 as a target of MLD-STZ toxicity; Mechanism responsible for the STZ-induced reduction of GLUT2 protein and messenger RNA.