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Title: Effects of Sustained Treatment With Lixisenatide on Gastric Emptying and Postprandial Glucose Metabolism in Type 2 Diabetes: A Randomized Controlled Trial.
Authors: Rayner, Christopher K; Watson, Linda E; Phillips, Liza K; Lange, Kylie; Bound, Michelle J; Grivell, Jacqueline; Wu, Tongzhi; Jones, Karen L; Horowitz, Michael; Ferrannini, Ele; Tricò, Domenico; Frascerra, Silvia; Mari, Andrea; Natali, Andrea
Abstract: Tachyphylaxis for slowing of gastric emptying is seen with continuous exposure to glucagon-like peptide 1 (GLP-1). We therefore aimed to establish whether prolonged use of a "short-acting" GLP-1 receptor agonist, lixisenatide, achieves sustained slowing of gastric emptying and reduction in postprandial glycemia.
Publication: Diabetes care, 2020, Vol 43, Issue 8, p1813
ISSN: 1935-5548
Publication type: Journal Article
DOI: 10.2337/dc20-0190

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Effects of Sustained Treatment With Lixisenatide on Gastric Emptying and Postprandial Glucose Metabolism in Type 2 Diabetes: A Randomized Controlled Trial.