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- Title
Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver.
- Authors
Lehmann, Rainer; Franken, Holger; Dammeier, Sascha; Rosenbaum, Lars; Kantartzis, Konstantinos; Peter, Andreas; Zell, Andreas; Adam, Patrick; Li, Jia; Xu, Guowang; Königsrainer, Alfred; Machann, Jürgen; Schick, Fritz; Hrabé de Angelis, Martin; Schwab, Matthias; Staiger, Harald; Schleicher, Erwin; Gastaldelli, Amalia; Fritsche, Andreas; Häring, Hans-Ulrich; Stefan, Norbert
- Abstract
Nonalcoholic fatty liver (NAFL) is thought to contribute to insulin resistance and its metabolic complications. However, some individuals with NAFL remain insulin sensitive. Mechanisms involved in the susceptibility to develop insulin resistance in humans with NAFL are largely unknown. We investigated circulating markers and mechanisms of a metabolically benign and malignant NAFL by applying a metabolomic approach.
- Publication
Diabetes care, 2013, Vol 36, Issue 8, p2331
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc12-1760