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- Title
Neural correlates of stress- and food cue-induced food craving in obesity: association with insulin levels.
- Authors
Jastreboff, Ania M; Sinha, Rajita; Lacadie, Cheryl; Small, Dana M; Sherwin, Robert S; Potenza, Marc N
- Abstract
Obesity is associated with alterations in corticolimbic-striatal brain regions involved in food motivation and reward. Stress and the presence of food cues may each motivate eating and engage corticolimibic-striatal neurocircuitry. It is unknown how these factors interact to influence brain responses and whether these interactions are influenced by obesity, insulin levels, and insulin sensitivity. We hypothesized that obese individuals would show greater responses in corticolimbic-striatal neurocircuitry after exposure to stress and food cues and that brain activations would correlate with subjective food craving, insulin levels, and HOMA-IR.
- Publication
Diabetes care, 2013, Vol 36, Issue 2, p394
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc12-1112