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- Title
High-dose aspirin is required to influence plasma fibrin network structure in patients with type 1 diabetes.
- Authors
Tehrani, Sara; Antovic, Aleksandra; Mobarrez, Fariborz; Mageed, Koteiba; Lins, Per-Eric; Adamson, Ulf; Wallén, Håkan N; Jörneskog, Gun
- Abstract
Patients with type 1 diabetes form a less permeable fibrin network, which could contribute to their increased risk of cardiovascular disease (CVD). Low-dose aspirin treatment is the standard in the management of CVD; however, the effect seems reduced in patients with diabetes. We investigated the effects of low- and high-dose aspirin treatment on fibrin network formation in patients with type 1 diabetes (primary aim) and the possible interaction between the treatment effects of aspirin on fibrin network permeability and glycemic control in these patients (secondary aim).
- Publication
Diabetes care, 2012, Vol 35, Issue 2, p404
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc11-1302