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- Title
The alteration of aspart insulin pharmacodynamics when mixed with detemir insulin.
- Authors
Cengiz, Eda; Swan, Karena L; Tamborlane, William V; Sherr, Jennifer L; Martin, Melody; Weinzimer, Stuart A
- Abstract
Mixing rapid acting insulin analogs with detemir insulin to minimize daily injections has been adopted as a common regimen, especially for some children with type 1 diabetes, despite the manufacturing company's caution against mixing these analogs in the same syringe. The effect of this practice on the pharmacodynamics (PD) of rapid-acting insulin has not been widely studied. This crossover, randomized study was undertaken to determine whether mixing aspart with detemir insulin has an adverse effect on the early glucodynamic action of rapid-acting insulin analog in humans.
- Publication
Diabetes care, 2012, Vol 35, Issue 4, p690
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc11-0732