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- Title
Identification of autoantibody-negative autoimmune type 2 diabetic patients.
- Authors
Brooks-Worrell, Barbara M; Reichow, Jessica L; Goel, Amit; Ismail, Heba; Palmer, Jerry P
- Abstract
Islet autoimmunity has long been recognized in the pathogenesis of type 1 diabetes and is becoming increasingly acknowledged as a component in the pathogenesis of type 2 diabetes. Islet reactive T cells and autoantibodies have been demonstrated in type 1 diabetes, whereas islet autoimmunity in type 2 diabetes has been limited to islet autoantibodies. In this study, we investigated whether islet reactive T cells might also be present in type 2 diabetic patients and how islet reactive T cells correlate with β-cell function.
- Publication
Diabetes care, 2011, Vol 34, Issue 1, p168
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc10-0579