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- Title
Abnormal LDIflare but normal quantitative sensory testing and dermal nerve fiber density in patients with painful diabetic neuropathy.
- Authors
Krishnan, Singhan T M; Quattrini, Cristian; Jeziorska, Maria; Malik, Rayaz A; Rayman, Gerry
- Abstract
Abnormal small nerve fiber function may be an early feature of diabetic neuropathy and may also underlie painful symptoms. Methods for assessing small-fiber damage include quantitative sensory testing (QST) and determining intraepidermal nerve fiber density. We recently described a reproducible physiological technique, the LDIflare, which assesses small-fiber function and thus may reflect early dysfunction before structural damage. The value of this technique in painful neuropathy was assessed by comparing it with QST and dermal nerve fiber density (NFD).
- Publication
Diabetes care, 2009, Vol 32, Issue 3, p451
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc08-1453