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- Title
Elevated levels of the anti-inflammatory interleukin-1 receptor antagonist precede the onset of type 2 diabetes: the Whitehall II study.
- Authors
Herder, Christian; Brunner, Eric J; Rathmann, Wolfgang; Strassburger, Klaus; Tabák, Adam G; Schloot, Nanette C; Witte, Daniel R
- Abstract
Interleukin-1 receptor antagonist (IL-1Ra), a natural inhibitor of interleukin-1 beta, has been shown to improve beta-cell function and glycemic control in patients with type 2 diabetes. The aim of this study was to investigate whether baseline systemic levels of IL-1Ra are associated with incident type 2 diabetes during more than 10 years of follow-up.
- Publication
Diabetes care, 2009, Vol 32, Issue 3, p421
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc08-1161