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- Title
Degree of obesity and glucose allostasis are major effectors of glucose tolerance dynamics in obese youth.
- Authors
Weiss, Ram; Cali, Anna M; Dziura, James; Burgert, Tania S; Tamborlane, William V; Caprio, Sonia
- Abstract
One of the signals for the beta-cell to maintain an adequate response to worsening insulin sensitivity is elevated ambient glycemia, namely the concept of "glucose allostasis." We examined whether glucose allostasis can be demonstrated using oral glucose tolerance tests (OGTTs) and the effects of the dynamics of beta-cell demand on longitudinal changes of glucose tolerance in obese youth.
- Publication
Diabetes care, 2007, Vol 30, Issue 7, p1845
- ISSN
1935-5548
- Publication type
Journal Article
- DOI
10.2337/dc07-0325