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- Title
Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes.
- Authors
Pflueger, Maren; Seppänen-Laakso, Tuulikki; Suortti, Tapani; Hyötyläinen, Tuulia; Achenbach, Peter; Bonifacio, Ezio; Orešič, Matej; Ziegler, Anette-G
- Abstract
Islet autoimmunity precedes type 1 diabetes and often initiates in childhood. Phenotypic variation in islet autoimmunity relative to the age of its development suggests heterogeneous mechanisms of autoimmune activation. To support this notion, we examined whether serum metabolite profiles differ between children with respect to islet autoantibody status and the age of islet autoantibody development.
- Publication
Diabetes, 2011, Vol 60, Issue 11, p2740
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db10-1652