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Title
Stepwise or linear decrease in penetrance of type 1 diabetes with lower-risk HLA genotypes over the past 40 years.
Authors
Steck, Andrea K; Armstrong, Taylor K; Babu, Sunanda R; Eisenbarth, George S; Type 1 Diabetes Genetics Consortium
Abstract
The objective of this study was to test if the proportion of new-onset diabetic subjects with the HLA-DR3/4-DQB1*0302 genotype is decreasing over time.