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- Title
Effects of metformin on body weight and body composition in obese insulin-resistant children: a randomized clinical trial.
- Authors
Yanovski, Jack A; Krakoff, Jonathan; Salaita, Christine G; McDuffie, Jennifer R; Kozlosky, Merel; Sebring, Nancy G; Reynolds, James C; Brady, Sheila M; Calis, Karim A
- Abstract
Metformin can decrease adiposity and ameliorate obesity-related comorbid conditions, including abnormalities in glucose homeostasis in adolescents, but there are few data evaluating the efficacy of metformin among younger children. Our objective was to determine whether metformin treatment causes weight loss and improves obesity-related comorbidities in obese children, who are insulin-resistant.
- Publication
Diabetes, 2011, Vol 60, Issue 2, p477
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db10-1185