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- Title
Association of a fasting glucose genetic risk score with subclinical atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study.
- Authors
Rasmussen-Torvik, Laura J; Li, Man; Kao, Wen H; Couper, David; Boerwinkle, Eric; Bielinski, Suzette J; Folsom, Aaron R; Pankow, James S
- Abstract
Elevated fasting glucose level is associated with increased carotid intima-media thickness (IMT), a measure of subclinical atherosclerosis. It is unclear if this association is causal. Using the principle of Mendelian randomization, we sought to explore the causal association between circulating glucose and IMT by examining the association of a genetic risk score with IMT.
- Publication
Diabetes, 2011, Vol 60, Issue 1, p331
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db10-0839