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- Title
Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents.
- Authors
Goran, Michael I; Walker, Ryan; Le, Kim-Anne; Mahurkar, Swapna; Vikman, Susanna; Davis, Jaimie N; Spruijt-Metz, Donna; Weigensberg, Marc J; Allayee, Hooman
- Abstract
A genome-wide study of adults identified a variant of PNPLA3 (rs738409) associated with ∼twofold higher liver fat. The purpose of this study was to examine the influence of PNPLA3 genotype on liver fat and other related metabolic outcomes in obese Hispanic children and adolescents.
- Publication
Diabetes, 2010, Vol 59, Issue 12, p3127
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db10-0554