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- Title
Targeted disruption of pancreatic-derived factor (PANDER, FAM3B) impairs pancreatic beta-cell function.
- Authors
Robert-Cooperman, Claudia E; Carnegie, Jason R; Wilson, Camella G; Yang, Jichun; Cook, Joshua R; Wu, Jianmei; Young, Robert A; Wolf, Bryan A; Burkhardt, Brant R
- Abstract
Pancreatic-derived factor (PANDER, FAM3B) is a pancreatic islet-specific cytokine-like protein that is secreted from beta-cells upon glucose stimulation. The biological function of PANDER is unknown, and to address this we generated and characterized a PANDER knockout mouse.
- Publication
Diabetes, 2010, Vol 59, Issue 9, p2209
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db09-1552