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- Title
Gene variants of TCF7L2 influence weight loss and body composition during lifestyle intervention in a population at risk for type 2 diabetes.
- Authors
Haupt, Axel; Thamer, Claus; Heni, Martin; Ketterer, Caroline; Machann, Jürgen; Schick, Fritz; Machicao, Fausto; Stefan, Norbert; Claussen, Claus D; Häring, Hans-Ulrich; Fritsche, Andreas; Staiger, Harald
- Abstract
The impact of the diabetes risk gene transcription factor 7-like 2 (TCF7L2) on body weight is unclear. As TCF7L2 is expressed in adipose tissue and involved in Wnt-dependent regulation of adipogenesis, we studied the impact of TCF7L2 variants on body composition and weight loss during lifestyle intervention.
- Publication
Diabetes, 2010, Vol 59, Issue 3, p747
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db09-1050