We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function.
- Authors
Lau, Janet; Hebrok, Matthias
- Abstract
Current studies indicate that Hedgehog (Hh) signaling must be excluded during early stages of pancreas formation. However, conflicting evidence suggests that Hh signaling may be active later during pancreas formation and that it is required for insulin production and secretion in cultured beta-cell lines. The objective of this study was to address these discrepancies by assessing the in vivo role of epithelial Hh signaling in the pancreas.
- Publication
Diabetes, 2010, Vol 59, Issue 5, p1211
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db09-0914