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Title
Expansion of human regulatory T-cells from patients with type 1 diabetes.
Authors
Putnam, Amy L; Brusko, Todd M; Lee, Michael R; Liu, Weihong; Szot, Gregory L; Ghosh, Taumoha; Atkinson, Mark A; Bluestone, Jeffrey A
Abstract
Regulatory T-cells (Tregs) have catalyzed the field of immune regulation. However, translating Treg-based therapies from animal models of autoimmunity to human clinical trials requires robust methods for the isolation and expansion of these cells-a need forming the basis for these studies.