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Title
Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice.
Authors
Ku, Ching-Hsin; White, Kathryn E; Dei Cas, Alessandra; Hayward, Anthea; Webster, Zoe; Bilous, Rudy; Marshall, Sally; Viberti, Giancarlo; Gnudi, Luigi
Abstract
Podocyte-specific, doxycycline (DOX)-inducible overexpression of soluble vascular endothelial growth factor (VEGF) receptor-1 (sFlt-1) in adult mice was used to investigate the role of the VEGF-A/VEGF receptor (VEGFR) system in diabetic glomerulopathy.