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- Title
Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening.
- Authors
Barker, Jennifer M; Triolo, Taylor M; Aly, Theresa A; Baschal, Erin E; Babu, Sunanda R; Kretowski, Adam; Rewers, Marian J; Eisenbarth, George S
- Abstract
People with the HLA genotype DRB1*0301-DQA1*0501-DQB1*0201/DRB1*04-DQA1*0301-DQB1*0302 (DR3/4-DQ8) are at the highest risk of developing type 1 diabetes. We sought to find an inexpensive, rapid test to identify DR3/4-DQ8 subjects using two single nucleotide polymorphisms (SNPs).
- Publication
Diabetes, 2008, Vol 57, Issue 11, p3152
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db08-0605