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- Title
Intrahepatic glucose flux as a mechanism for defective intrahepatic islet alpha-cell response to hypoglycemia.
- Authors
Zhou, Huarong; Zhang, Tao; Bogdani, Marika; Oseid, Elizabeth; Parazzoli, Susan; Vantyghem, Marie-Christine; Harmon, Jamie; Slucca, Michela; Robertson, R Paul
- Abstract
Glucagon responses to hypoglycemia from islets transplanted in the liver are defective. To determine whether this defect is related to intrahepatic glycogen, islets from inbred Lewis rats were transplanted into the hepatic sinus (H group), peritoneal cavity (P group), omentum (O group), and kidney capsule (K group) of recipient Lewis rats previously rendered diabetic with streptozotocin (STZ).
- Publication
Diabetes, 2008, Vol 57, Issue 6, p1567
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db08-0137