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- Title
Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood.
- Authors
Edghill, Emma L; Flanagan, Sarah E; Patch, Ann-Marie; Boustred, Chris; Parrish, Andrew; Shields, Beverley; Shepherd, Maggie H; Hussain, Khalid; Kapoor, Ritika R; Malecki, Maciej; MacDonald, Michael J; Støy, Julie; Steiner, Donald F; Philipson, Louis H; Bell, Graeme I; Hattersley, Andrew T; Ellard, Sian; Neonatal Diabetes International Collaborative Group
- Abstract
Insulin gene (INS) mutations have recently been described as a cause of permanent neonatal diabetes (PND). We aimed to determine the prevalence, genetics, and clinical phenotype of INS mutations in large cohorts of patients with neonatal diabetes and permanent diabetes diagnosed in infancy, childhood, or adulthood.
- Publication
Diabetes, 2008, Vol 57, Issue 4, p1034
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db07-1405