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- Title
Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse.
- Authors
Juhl, Kirstine; Sarkar, Suparna A; Wong, Randall; Jensen, Jan; Hutton, John C
- Abstract
To document the transcriptome of the pancreatic islet during the early and late development of the mouse pancreas and highlight the qualitative and quantitative features of gene expression that contribute to the specification, growth, and differentiation of the major endocrine cell types. A further objective was to identify endocrine cell biomarkers, targets of diabetic autoimmunity, and regulatory pathways underlying islet responses to physiological and pathological stimuli.
- Publication
Diabetes, 2008, Vol 57, Issue 10, p2755
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db07-1126