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- Title
Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.
- Authors
Højlund, Kurt; Glintborg, Dorte; Andersen, Nicoline R; Birk, Jesper B; Treebak, Jonas T; Frøsig, Christian; Beck-Nielsen, Henning; Wojtaszewski, Jørgen F P
- Abstract
Insulin resistance in skeletal muscle is a major risk factor for type 2 diabetes in women with polycystic ovary syndrome (PCOS). However, the molecular mechanisms underlying skeletal muscle insulin resistance and the insulin-sensitizing effect of thiazolidinediones in PCOS in vivo are less well characterized.
- Publication
Diabetes, 2008, Vol 57, Issue 2, p357
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db07-0706