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- Title
Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation.
- Authors
Simon, Greg; Parker, Matthew; Ramiya, Vijayakumar; Wasserfall, Clive; Huang, Yanfei; Bresson, Damien; Schwartz, R Fletcher; Campbell-Thompson, Martha; Tenace, Lauren; Brusko, Todd; Xue, Song; Scaria, Abraham; Lukason, Michael; Eisenbeis, Scott; Williams, John; Clare-Salzler, Michael; Schatz, Desmond; Kaplan, Bruce; Von Herrath, Matthias; Womer, Karl; Atkinson, Mark A
- Abstract
Antilymphocyte serum can reverse overt type 1 diabetes in NOD mice; yet, the therapeutic parameters and immunological mechanisms underlying the ability for this agent to modulate autoimmune responses against beta-cells are unclear, forming the rationale for this investigation.
- Publication
Diabetes, 2008, Vol 57, Issue 2, p405
- ISSN
1939-327X
- Publication type
Journal Article
- DOI
10.2337/db06-1384