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- Title
Molecular Switches Regulating Assembly Transitions of Biological Molecules: Tubulin, Amylin and Lipids.
- Authors
DAE-WOONG JEONG; SUHO LEE; JUNCHEOL LEE; HYUNWOO JANG; SUNGMUN LEE; MYUNG CHUL CHOI
- Abstract
This article presents recent works developing a fundamental understanding of structures and interactions of supramolecular assemblies of biological molecules, in particular, tubulin, amylin and lipids, of which the assembly transition is regulated by molecular switches - tau, taxol, cholesterol, SPAN 80 and lipoic/ascorbic acids. Nanometer to many micrometer scaled structures are solved by combining reciprocal space and real space data resulting from X-ray scattering/reflectivity, fluorescence and electron microscopy.
- Subjects
BIOMOLECULES; TUBULINS; MOLECULAR switches; AMYLIN; LIPIDS; X-ray scattering
- Publication
AAPPS Bulletin, 2019, Vol 29, Issue 5, p52
- ISSN
0218-2203
- Publication type
Academic Journal
- DOI
10.22661/AAPPSbl.2019.29.5.52